tomas.infer.heteroDbl

tomas.infer.heteroDbl(adata, d_groupby, ct_groupby, de_sorted=None, dbl_groupby='heteroDbl', vis=False)

Identification and refinement of heterotypic doublets

Parameters:

• adata (AnnData) – UMI matrix of all droplet population.

• d_groupby (str) – The key of the droplet annotation (‘Homotypic’ or ‘Heterotypic’) results stored in adata.obs.

• ct_groupby (str) – The key of the cell type annotation results stored in adata.obs.

• de_sorted (data frame, optional) – Output of function ‘extract_specific_genes’. The default is None.

• dbl_groupby (TYPE, optional) – DESCRIPTION. The default is ‘heteroDbl’.

• vis (bool, optional) – Whether to visualize the heterodlb identification results. The default is True.

Return type:

None. Identified heterotypic